Impurities

Afatinib Impurities

  • Afatinib Impurity A

  • Impurity: Afatinib EP Impurity A
  • Chemical Name: (R)-N-(3-chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine
  • Afatinib Impurity B

  • Impurity: Afatinib EP Impurity B
  • Chemical Name: N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine
  • Afatinib Impurity C

  • Impurity: Afatinib EP Impurity C
  • Chemical Name: (R,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
  • Afatinib Impurity D

  • Impurity: Afatinib EP Impurity D
  • Chemical Name: (S,Z)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide

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