Dolutegravir Impurities

  • Dolutegravir-4-fluoro impurity

  • Impurity: Dolutegravir-4-fluoro impurity
  • CAS No: N/A
  • Chemical Name: (4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

  • Dolutegravir-2-fluoro impurity

  • Impurity: Dolutegravir-2-fluoro impurity
  • CAS No: N/A
  • Chemical Name: (4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

  • Dolutegravir Impurities

  • Impurity: Dolutegravir In House Impurity 1
  • CAS No: N/A
  • Chemical Name: (R)-2-(3-Hydroxy-1-methyl-propyl)-9-methoxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid

  • Dolutegravir Impurities

  • Impurity: Dolutegravir In House Impurity 2
  • CAS No: N/A
  • Chemical Name: (R)-2-(3-Hydroxy-1-methyl-propyl)-9-methoxy-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxylic acid 2,4-difluoro-benzylamide

  • Dolutegravir Impurities

  • Impurity: Dolutegravir In House Impurity 3
  • CAS No: N/A
  • Chemical Name: (S)-N-(2,4-difluorobenzyl)-7-methoxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro2Hpyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

  • Dolutegravir Impurities

  • Impurity: Dolutegravir 2-Fluoro (4-Desfluoro Impurity )
  • CAS No: N/A
  • Chemical Name: (4R,12aS)-N-(2-fluoro benzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1’,2’:4,5] pyrazino[2,1-b][1,3] oxazine-9-carboxamide.

  • Dolutegravir Impurities

  • Impurity: Dolutegravir 2,3-Fluoro Impurity
  • CAS No: N/A
  • Chemical Name: (4R,12aS)-N-(2,3-Difluoro benzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1’,2’:4,5] pyrazino[2,1-b][1,3] oxazine-9-carboxamide.

  • Dolutegravir Impurities

  • Impurity: Dolutegravir 2,5-Fluoro Impurity
  • CAS No: N/A
  • Chemical Name: (4R,12aS)-N-(2,5-Difluoro benzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide.

  • Dolutegravir Impurities

  • Impurity: Dolutegravir -4-Fluoro (Dolutegravir 2-Desfluoro Impurity
  • CAS No: N/A
  • Chemical Name: (4R,12aS)-N-(4-fluoro benzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

  • Dolutegravir Impurities

  • Impurity: Dolutegravir (R,R)-Isomer (Dolutegravir Diasteriomer- 01)
  • CAS No: N/A
  • Chemical Name: (4R,12aR)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

  • Dolutegravir Impurities

  • Impurity: Dolutegravir (S,R)-Isomer )Dolutegravir Enantiomer)
  • CAS No: N/A
  • Chemical Name: (4S,12aR)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

  • Dolutegravir Impurities

  • Impurity: Dolutegravir 2,6-Difluoro Impurity
  • CAS No: N/A
  • Chemical Name: 5-Hydroxy-4-methyl-6,10-dioxo-3,4,6,9,9a,10-hexahydro-2H,8aH-1-oxa-4a-aza-anthracene-7-carboxylic acid 2,6-difluoro-benzylamide